Gjertrud Laurell

Post Docs

Contact

Position:: Post Doc

Address:: Dept. Neurology and Neurobiology Research Unit,
Copenhagen University Hospital, Rigshospitalet,
Building 8057,
Blegdamsvej 9, DK-2100 Copenhagen, Denmark
Email:: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone:: 3545 6741

Curriculum vitae

Curriculum vitae

Scientific interests

My main scientific interest is pharmacokinetic modelling of nuclear imaging data, especially in the context of positron emission tomography (PET) of the brain. I am particularly interested in models that reduce the costs and complexity of PET experiments, as well as models that quantify tracer displacement following a within-scan challenge. By evaluating models and their underlying assumptions, I hope to make PET neuroimaging studies more reliable and informative.

Biography

2026 -	Postdoctoral Researcher at the Neurobiology Research Unit
2024 - 2026	Paul Janssen Fellow in Translational Neuroscience Resarch at Columbia University
2023 - 2024	Postdoctoral Researcher at Columbia University
2020 - 2023	PhD student at the Neurobiology Research Unit and University of Copenhagen
2019 - 2020	Research Assistant at the Neurobiology Research Unit
2016 - 2018	Master student in Medical Nuclide Techniques, Uppsala University
2013 - 2016	Bachelor student in Engineering Physics, Uppsala University

Publications

https://scholar.google.com/citations?user=xiBDfhkAAAAJ&hl

Full-length research papers published in peer-reviewed journals:

Zanderigo F, Laurell GL, Doubrovin M, Molotkov A, Ali A, Arevalo RF, Solingapuram Sai KK, Mann JJ, Mintz A. Imaging microtubule dynamics in vivo in human brain: Optimal quantification based on a test-retest study. Journal of Nuclear Medicine. 2026 (online ahead of print). DOI: https://doi.org/10.2967/jnumed.125.271335
Varlow C, Madsen CA, Jaworski C, Laurell GL, Shulganov V, Skjøth-Rasmussen J, Nasser A, Schirmacher R, Knudsen GM. Kinetic modelling and evaluation of the TrkA/B/C radioligand [18F]TRACK in the pig brain. Nuclear Medicine and Biology. 2026;152-153:109600. DOI: 10.1016/j.nucmedbio.2025.109600
Marstrand-Jørgensen MR, Laurell GL, Herrman S, Nasser A, Johansen A, Lund A, Andersen TL, Knudsen GM, Pinborg LH, Assessment of cerebral drug occupancy in humans using a single PET scan: A [11C]UCB-J PET study, European Journal of Nuclear Medicine and Molecular Imaging. 2024;51(11):3292-3304. DOI: 10.1007/s00259-024-06759-x
Laurell GL, Plavén-Sigray P, Johansen A, Raval NR, Nasser A, Madsen CA, Madsen J, Hansen HD, Donovan LL, Knudsen GM, Lammertsma AL, Ogden RT, Svarer C, Schain M. Kinetic models for estimating occupancy from single-scan PET displacement studies. Journal of Cerebral Blood Flow & Metabolism. 2023;43(9):1544-1556. DOI:10.1177/0271678X231168591
Laurell GL, Plavén-Sigray P, Svarer C, Ogden RT, Knudsen GM, Schain M. Designing drug occupancy studies with PET neuroimaging: Sample size, occupancy ranges and analytical methods. NeuroImage. 2022;263:119620. DOI: 10.1016/j.neuroimage.2022.119620
Laurell GL, Plavén-Sigray P, Jucaite A, Varrone A, Cosgrove KP, Svarer C, Knudsen GM, Karolinska Schizophrenia Project Consortium, Ogden RT, Zanderigo F, Cervenka S, Hillmer AT, Schain M. Nondisplaceable binding is a potential confounding factor in 11C-PBR28 translocator PET studies. Journal of Nuclear Medicine. 2021; 62:412-417. DOI: 10.2967/jnumed.120.243717

Awards

2024 - The Paul Janssen Fellowship in Translational Neuroscience (USD 146,000), awarded by Columbia University Department of Psychiatry.

2022 – Alavi-Mandell Award (USD 150)

2020 - Introductory research stipend (DKK 480,000), awarded by Rigshospitalet Research Council